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PhD, University of Wales, Swansea, 1985
MSc, Nankai University, 1988
BS, Henan Normal University, 1997
Mechanisms of DNA damage repair and mutagenesis
Cell and Molecular Biology
Awards & Honors
2019 Dean's Teacher Merit Honor Roll
2018 Dean's Teacher Merit Honor Roll
2017 Dean's Teacher Merit Honor Roll
2015 Faculty Distinguished Scholar Award
2009 Pfizer Award for Research Excellence
Geijer, M. E., Zhou, D., Selvam, K., Steurer, B., Mukherjee, C., Evers, B., Cugusi, S., van Toorn, M., van der Woude, M., Janssens, R., Kok, Y. P., Gong, W., Raams, A., Lo, C., Lebbink, J. H. G.; Geverts, B.; Plummer, D. A.; Bezstarosti, K.; Theil, A. F.; Mitter, R.; Houtsmuller, A. B., Vermeulen, W., Demmers, J. A. A., Li, S., van Vugt, M. A. T. M., Lans, H., Bernards, R., Svejstrup, J. Q., Chaudhuri, A. R., Wyrick, J. J., Marteijn, J. A. (2021) Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability. Nat. Cell Biol 23, 608–619.
Selvam, K., Rahman, S.A., Forrester, D., Bao, A., Lieu, M. and Li, S. (2020) Histone H4 LRS mutations can attenuate UV mutagenesis without affecting PCNA ubiquitination or sumoylation. DNA Repair 95, 102959.
Ko, T. Sharma, R. and Li, S. (2020) Genome-wide screening identifies novel genes implicated in cellular sensitivity to BRAFV600E expression. Oncogene 39, 723-738.
Ko, T. and Li, S (2019) Genome-wide screening identifies novel genes and biological processes implicated in cisplatin resistance. FASEB J. 33, 7143-7154.
Selvam, K., Rahman, S. A. and Li, S. (2019) Histone H4 H75E mutation attenuates global genomic and Rad26-independent transcription-coupled nucleotide excision repair. Nucleic Acids Res. 47, 7392-7401.
Selvam, K., Ding, B., Sharma, R. and Li, S. (2019) Evidence that moderate eviction of Spt5 and promotion of error-free transcriptional bypass by Rad26 facilitates transcription coupled repair. J. Mol. Biol. 431, 1322-1338.
Li, W. and Li, S. (2017) Facilitators and repressors of transcription coupled DNA repair in Saccharomyces cerevisiae. Photochem. Photobiol. 93, 259-267.
Li, W., Selvam, K., Rahman, S. A. and Li, S. (2016) Sen1, the yeast homolog of human senataxin, plays a more direct role than Rad26 in transcription coupled DNA repair. Nucleic Acids Res. 44, 6794-6802.
Li, S. (2015). Transcription coupled nucleotide excision repair in the yeast Saccharomyces cerevisiae: the ambiguous role of Rad26. DNA Repair 36, 43-48.
Li, M., Ko, T. and Li, S. (2015). High-resolution digital mapping of N-methylpurines in human cells reveals modulation of their induction and repair by nearest-neighbor nucleotides. J. Biol. Chem. 290, 23148–23161.
NSF, MCB-2102072, Li, Shisheng (PI), Regulation of transcription coupled DNA repair, 07/01/2021-06/30/2024
NIH/NIEHS (1R03ES033789), Li, Shisheng (PI), Implication of histone H4 LRS mutations in translesion synthesis and UV mutagenesis, 12/1/2021-11/30/2023
NSF, MCB-1615550, Li, Shisheng (PI), The role of Sen1 in transcription coupled DNA
NSF, MCB-1244019, Li, Shisheng (PI), Dot1 and histone H3 K79 methylation in nucleotide
02/01/2013 – 01/31/2017